Searchable abstracts of presentations at key conferences in endocrinology

ea0038p142 | Growth and development | SFEBES2015

Human foetal adrenal gland development and effects of maternal smoking

Johnston Zoe C , Filis Panagiotis , Bellingham Michelle , O'Shaughnessy Peter J , Fowler Paul A

Introduction: The human foetal adrenal gland (HFA) is a highly active endocrine organ, producing large amounts of DHEA and DHEAS. Our understanding of HFA development is limited, however, and species differences mean that animal models are only of partial use. Maternal cigarette smoking is known to increase the post-natal risk of health complications of the foetus, and the mechanisms involved may include effects on the HFA.Aim: To examine normal HFA deve...